Research workbench
Tfiiia finger 1-3 bound to DNA, NMR, 22 structures
Analyse Tfiiia finger 1-3 bound to DNA, NMR, 22 structures in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1TF3
- Type
- protein + DNA
- Length
- 122 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5S RNA gene; Transcription factor iiia
- UniProt
- P03001
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.52
Structure
solution nmr · 3 distinct chains · 39% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | 5S RNA gene | dna | 15 | — | — |
| F | 5S RNA gene | dna | 15 | — | — |
| A | Transcription factor iiia | protein | 92 | 39% helix, 13% strand | P03001 |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.52 | 0.84 | 15 | empty |
| 2 | 109 | 0.36 | 0.74 | 15 | empty |
Interfaces
3 interfaces between chains.
- E–A · 960 Ų buried · 28 hydrogen bonds · protein-nucleic
- F–A · 787 Ų buried · 13 hydrogen bonds · protein-nucleic
- E–F · 689 Ų buried · 82 hydrogen bonds · nucleic-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03001
- Elsewhere: RCSB PDB 1TF3 · PDBe 1TF3 · UniProt P03001
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