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Drosophila tbp associated factors DTAFII42/DTAFII62 heterotetramer

Analyse Drosophila tbp associated factors DTAFII42/DTAFII62 heterotetramer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1TAF
Type
protein
Length
138 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Tfiid tbp associated factor 42; Tfiid tbp associated factor 62
UniProt
Q27272, P49847
Ligands
ZN

Structure

x-ray diffraction · 2 distinct chains · 69% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATfiid tbp associated factor 42protein6872% helix, 3% strandQ27272
BTfiid tbp associated factor 62protein7066% helix, 3% strandP49847

Ligands and binding sites

  • ZN · Zinc ion · metal · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 1737 Ų buried · 18 hydrogen bonds · protein-protein

Compared structures

  • 1TAF · Drosophila tbp associated factors DTAFII42/DTAFII62 heterotetramer · the same entry in another collection · chain A against A, TM-score 1.00
  • Q27272 · AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 9… · a predicted model of the same protein · chain A against A, TM-score 0.91
  • P49847 · AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 6… · a predicted model of the same protein · chain B against A, TM-score 0.90

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