Research workbench
Unknown conserved bacterial protein from pseudomonas aeruginosa PAO1
Analyse Unknown conserved bacterial protein from pseudomonas aeruginosa PAO1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1T3U
- Type
- protein
- Length
- 368 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein
- UniProt
- Q9HTW3
- Pockets
- 7 · best druggability 0.55
Structure
x-ray diffraction · 3 distinct chains · 70% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Conserved hypothetical protein | protein | 92 | 71% helix, 11% strand | Q9HTW3 |
| B | Conserved hypothetical protein | protein | 93 | 67% helix, 15% strand | Q9HTW3 |
| D | Conserved hypothetical protein | protein | 91 | 71% helix, 11% strand | Q9HTW3 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.55 | 0.80 | 27 | empty |
| 2 | 142 | 0.52 | 0.80 | 18 | empty |
| 3 | 67 | 0.41 | 0.80 | 8 | empty |
| 4 | 111 | 0.38 | 0.74 | 15 | empty |
| 5 | 81 | 0.36 | 0.76 | 17 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1676 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 1653 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 471 Ų buried · 5 hydrogen bonds · protein-protein
- A–D · 463 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 447 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 1T3U · Unknown conserved bacterial protein from Pseudomonas aeruginosa PAO1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HTW3 · AlphaFold monomer V2.0 prediction for cell division protein zapa (Q9HTW3) · a predicted model of the same protein · chain D against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HTW3
- Elsewhere: RCSB PDB 1T3U · PDBe 1T3U · UniProt Q9HTW3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.