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Structure of the adaptor protein P14 reveals a profilin-like fold with novel function

Analyse Structure of the adaptor protein P14 reveals a profilin-like fold with novel… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SZV
Type: protein
Length: 125 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Late ENDOSOMAL/LYSOSOMAL MP1 interacting protein
UniProt: Q9JHS3
Pockets: 1 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 27% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Late ENDOSOMAL/LYSOSOMAL MP1 interacting protein	protein	125	27% helix, 26% strand	Q9JHS3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.46	0.81	16	empty

Compared structures

1SZV · Structure of the Adaptor Protein p14 reveals a Profilin-like Fold with Novel Function · the same entry in another collection · chain A against A, TM-score 1.00
Q9JHS3 · AlphaFold monomer V2.0 prediction for ragulator complex protein LAMTOR2 (Q9JHS3) · a predicted model of the same protein · chain A against A, TM-score 0.53

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9JHS3
Elsewhere: RCSB PDB 1SZV · PDBe 1SZV · UniProt Q9JHS3

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