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Crystal structure of human BET3

Analyse Crystal structure of human BET3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SZ7
Type: protein
Length: 159 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trafficking protein particle complex subunit 3
UniProt: O43617
Ligands: PLM
Pockets: 1 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Trafficking protein particle complex subunit 3	protein	159	49% helix, 18% strand	O43617

Ligands and binding sites

PLM · Palmitic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	237	0.76	0.89	30	PLM

Modifications

Observed in the structure: 1 lipid (palmitoylation).

Compared structures

1SZ7 · Crystal structure of Human Bet3 · the same entry in another collection · chain A against A, TM-score 1.00
O43617 · AlphaFold monomer V2.0 prediction for trafficking protein particle complex subunit 3… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43617
Elsewhere: RCSB PDB 1SZ7 · PDBe 1SZ7 · UniProt O43617

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