Research workbench
Crystal structure of yan-SAM/MAE-SAM complex
Analyse Crystal structure of yan-SAM/MAE-SAM complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SV0
- Type
- protein
- Length
- 319 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ets DNA-binding protein pokkuri; Modulator of the activity of ets CG15085-pa
- UniProt
- Q01842, Q9I7G2
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 4 distinct chains · 62% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ets DNA-binding protein pokkuri | protein | 77 | 62% helix, 0% strand | Q01842 |
| B | Ets DNA-binding protein pokkuri | protein | 79 | 61% helix, 0% strand | Q01842 |
| C | Modulator of the activity of ets CG15085-pa | protein | 82 | 62% helix, 2% strand | Q9I7G2 |
| D | Modulator of the activity of ets CG15085-pa | protein | 81 | 63% helix, 0% strand | Q9I7G2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 279 | 0.53 | 0.75 | 35 | empty |
| 2 | 52 | 0.36 | 0.79 | 19 | empty |
| 3 | 64 | 0.26 | 0.72 | 21 | empty |
Interfaces
4 interfaces between chains.
- B–D · 522 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 505 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 281 Ų buried · 1 hydrogen bond · protein-protein
- B–C · 11 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01842
- Every structure of UniProt Q9I7G2
- Elsewhere: RCSB PDB 1SV0 · PDBe 1SV0 · UniProt Q01842 · UniProt Q9I7G2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.