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Solution structure of the second complement control protein (ccp) module of the GABA(B)R1A receptor, pro-119 cis conformer

Analyse Solution structure of the second complement control protein (ccp) module of the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SS2
Type: protein
Length: 68 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gamma-aminobutyric acid type B receptor, subunit 1
UniProt: Q9Z0U4
Pockets: 1 · best druggability 0.43

Structure

solution nmr · 1 distinct chain · 4% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gamma-aminobutyric acid type B receptor, subunit 1	protein	68	4% helix, 34% strand	Q9Z0U4

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.43	0.79	14	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1SS2 · Solution structure of the second complement control protein (CCP) module of the… · the same entry in another collection · chain A against A, TM-score 1.00
Q9Z0U4 · AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid type B receptor subunit 1… · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Z0U4
Elsewhere: RCSB PDB 1SS2 · PDBe 1SS2 · UniProt Q9Z0U4

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