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Crystal structure of signalling protein from SHEEP(SPS-40) at 3.0A resolution using crystal grown in the presence of polysaccharides
Analyse Crystal structure of signalling protein from SHEEP(SPS-40) at 3.0A resolution… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SR0
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Signal processing protein
- Ligands
- BMA, NAG, NDG
- Pockets
- 3 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal processing protein | protein | 361 | 35% helix, 24% strand | — |
Ligands and binding sites
- BMA · beta-D-mannopyranose · sugar · 3 copies
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 229 | 0.55 | 0.77 | 32 | empty |
| 2 | 182 | 0.55 | 0.79 | 25 | empty |
| 3 | 96 | 0.39 | 0.76 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 1SR0 · Crystal structure of signalling protein from sheep(SPS-40) at 3.0A resolution using… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1SR0 · PDBe 1SR0
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