Research workbench
Crystal structure of the chorismate synthase from campylobacter jejuni, northeast structural genomics target BR19
Analyse Crystal structure of the chorismate synthase from campylobacter jejuni… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SQ1
- Type
- protein
- Length
- 288 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chorismate synthase
- EC
- 4.2.3.5
- UniProt
- Q9PM41
- Ligands
- SO4
- Pockets
- 4 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chorismate synthase (EC 4.2.3.5) | protein | 288 | 36% helix, 23% strand | Q9PM41 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.51 | 0.80 | 24 | empty |
| 2 | 59 | 0.37 | 0.79 | 17 | empty |
| 3 | 74 | 0.36 | 0.77 | 20 | empty |
| 4 | 84 | 0.34 | 0.74 | 17 | empty |
Modifications
Observed in the structure: 7 modified (engineered).
Compared structures
- 1SQ1 · Crystal Structure of the Chorismate Synthase from Campylobacter jejuni, Northeast… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9PM41 · AlphaFold monomer V2.0 prediction for chorismate synthase (Q9PM41) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9PM41
- Elsewhere: RCSB PDB 1SQ1 · PDBe 1SQ1 · UniProt Q9PM41
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