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Three-dimensional structure of bombyxin-II, an insulin-related brain- secretory peptide of the silkmoth bombyx mori: comparison with insulin and relaxin

Analyse Three-dimensional structure of bombyxin-II, an insulin-related brain- secretory… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1BOM
Type
protein
Length
48 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Bombyxin-II,BOMBYXIN a-2; Bombyxin-II,BOMBYXIN a-6
UniProt
P15411, P26729

Structure

solution nmr · 2 distinct chains · 23% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ABombyxin-II,BOMBYXIN a-2protein2020% helix, 0% strandP15411
BBombyxin-II,BOMBYXIN a-6protein2825% helix, 0% strandP26729

Interfaces

1 interface between chains.

  • A–B · 462 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide, 1 modified (disulfide, cyclization).

Compared structures

  • 1BOM · Three-dimensional structure of bombyxin-II, an insulin-related brain-secretory peptide of… · the same entry in another collection · chain A against A, TM-score 1.00
  • P26729 · AlphaFold monomer V2.0 prediction for bombyxin a-6 (P26729) · a predicted model of the same protein · chain B against A, TM-score 0.47
  • P15411 · AlphaFold monomer V2.0 prediction for bombyxin a-2 (P15411) · a predicted model of the same protein · chain A against A, TM-score 0.29

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