Research workbench
Nucleotide-free diphtheria toxin
Analyse Nucleotide-free diphtheria toxin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SGK
- Type
- protein
- Length
- 523 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Diphtheria toxin (dimeric)
- EC
- 2.4.2.36
- UniProt
- P00588
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Diphtheria toxin (dimeric) (EC 2.4.2.36) | protein | 523 | 35% helix, 27% strand | P00588 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 311 | 0.57 | 0.76 | 29 | empty |
| 2 | 121 | 0.38 | 0.74 | 22 | empty |
| 3 | 57 | 0.35 | 0.79 | 15 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1SGK · Nucleotide-free diphtheria toxin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00588
- Elsewhere: RCSB PDB 1SGK · PDBe 1SGK · UniProt P00588
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