Research workbench
X-ray crystal structure of putative hth transcription regulator from archaeoglobus fulgidus
Analyse X-ray crystal structure of putative hth transcription regulator from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SFX
- Type
- protein
- Length
- 213 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein AF2008
- UniProt
- O28271
- Ligands
- CL
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 2 distinct chains · 62% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Conserved hypothetical protein AF2008 | protein | 109 | 60% helix, 14% strand | O28271 |
| B | Conserved hypothetical protein AF2008 | protein | 104 | 65% helix, 15% strand | O28271 |
Ligands and binding sites
- CL · Chloride ion · ion · 3 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.28 | 0.75 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 1444 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 1SFX · X-ray crystal structure of putative HTH transcription regulator from Archaeoglobus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28271
- Elsewhere: RCSB PDB 1SFX · PDBe 1SFX · UniProt O28271
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