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NMR solution structure of a parallel lna quadruplex

Analyse NMR solution structure of a parallel lna quadruplex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1S9L
Type
RNA
Length
20 nucleotides
Chains
4
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-((TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3'

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D5'-((TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3'rna5——

Interfaces

6 interfaces between chains.

  • A–B · 279 Ų buried · 15 hydrogen bonds · nucleic-nucleic
  • C–D · 277 Ų buried · 15 hydrogen bonds · nucleic-nucleic
  • A–C · 274 Ų buried · 14 hydrogen bonds · nucleic-nucleic
  • B–D · 273 Ų buried · 15 hydrogen bonds · nucleic-nucleic
  • A–D · 58 Ų buried · 0 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 20 modified (nucleotide modification).

Compared structures

  • 1S9L · NMR Solution Structure of a Parallel LNA Quadruplex · the same entry in another collection · chain A against A, TM-score 1.00

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