Research workbench

Crystal structure of the dead box protein DHH1P

Analyse Crystal structure of the dead box protein DHH1P in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1S2M
Type: protein
Length: 377 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative ATP-dependent RNA helicase DHH1
UniProt: P39517
Pockets: 3 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative ATP-dependent RNA helicase DHH1	protein	377	42% helix, 18% strand	P39517

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	221	0.55	0.78	35	empty
2	98	0.36	0.74	18	empty
3	61	0.33	0.77	13	empty

Compared structures

1S2M · Crystal Structure of the DEAD box protein Dhh1p · the same entry in another collection · chain A against A, TM-score 1.00
P39517 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DHH1 (P39517) · a predicted model of the same protein · chain A against A, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39517
Elsewhere: RCSB PDB 1S2M · PDBe 1S2M · UniProt P39517

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.