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Structure of the N-terminal domain of the adenylyl cyclase- associated protein (cap) from dictyostelium discoideum.
Analyse Structure of the N-terminal domain of the adenylyl cyclase- associated protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1S0P
- Type
- protein
- Length
- 352 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenylyl cyclase-associated protein
- UniProt
- P54654
- Ligands
- MG
- Pockets
- 2 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 76% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Adenylyl cyclase-associated protein | protein | 176 | 76% helix, 2% strand | P54654 |
Ligands and binding sites
- MG · Magnesium ion · metal · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 429 | 0.66 | 0.79 | 61 | MG |
| 2 | 344 | 0.60 | 0.77 | 45 | empty |
Interfaces
1 interface between chains.
- A–B · 713 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 1S0P · Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from… · the same entry in another collection · chain A against A, TM-score 1.00
- P54654 · AlphaFold monomer V2.0 prediction for adenylyl cyclase-associated protein (P54654) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54654
- Elsewhere: RCSB PDB 1S0P · PDBe 1S0P · UniProt P54654
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