Research workbench
A short lexitropsin that recognizes the DNA minor groove at 5'-actagt- 3': understanding the role of isopropyl-thiazole
Analyse A short lexitropsin that recognizes the DNA minor groove at 5'-actagt- 3'… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1RMX
- Type
- DNA
- Length
- 20 nucleotides
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3'
- Ligands
- AIK
Structure
solution nmr · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3' | dna | 10 | — | — |
Ligands and binding sites
- AIK · N-[3-(dimethylamino)propyl]-2-({[4-({[4-(formylamino)-1-methyl-1H-pyrrol-2-yl]carbonyl}amino)-1-methyl-1H-pyrrol-2-yl]carbonyl}amino)-5-isopropyl-1,3-thiazole-4-carboxamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 452 Ų buried · 67 hydrogen bonds · nucleic-nucleic
Compared structures
- 1RMX · A short lexitropsin that recognizes the DNA minor groove at 5'-actagt-3': understanding… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1RMX · PDBe 1RMX
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