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Intramolecular DNA triplex with RNA third strand, NMR, 10 structures

Analyse Intramolecular DNA triplex with RNA third strand, NMR, 10 structures in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1R3X
Type
DNA + RNA
Length
24 nucleotides
Chains
3
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*A)-3'); DNA (5'-D(*TP*TP*CP*TP*CP*TP*CP*T)-3'); RNA…

Structure

solution nmr · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*A)-3')dna8——
BDNA (5'-D(*TP*TP*CP*TP*CP*TP*CP*T)-3')dna8——
CRNA (5'-R(*UP*CP*UP*CP*UP*CP*UP*U)-3')rna8——

Interfaces

3 interfaces between chains.

  • A–C · 551 Ų buried · 45 hydrogen bonds · nucleic-nucleic
  • A–B · 376 Ų buried · 45 hydrogen bonds · nucleic-nucleic
  • B–C · 128 Ų buried · 3 hydrogen bonds · nucleic-nucleic

Compared structures

  • 1R3X · Intramolecular DNA triplex with RNA third strand, NMR, 10 structures · the same entry in another collection · chain A against A, TM-score 1.00

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