Research workbench
Crystal structure of apocalmodulin
Analyse Crystal structure of apocalmodulin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1QX5
- Type
- protein
- Length
- 1,159 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calmodulin
- UniProt
- P62161
- Pockets
- 20 · best druggability 0.72
Structure
x-ray diffraction · 4 distinct chains · 56% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, I, B, T, Y | Calmodulin | protein | 145 | 58% helix, 9% strand | P62161 |
| J | Calmodulin | protein | 144 | 58% helix, 7% strand | P62161 |
| K | Calmodulin | protein | 143 | 52% helix, 8% strand | P62161 |
| R | Calmodulin | protein | 147 | 55% helix, 8% strand | P62161 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 950 | 0.72 | 0.76 | 111 | empty |
| 2 | 671 | 0.71 | 0.78 | 85 | empty |
| 3 | 364 | 0.64 | 0.79 | 45 | empty |
| 4 | 309 | 0.64 | 0.80 | 35 | empty |
| 5 | 300 | 0.64 | 0.81 | 45 | empty |
Interfaces
20 interfaces between chains.
- J–T · 2710 Ų buried · 36 hydrogen bonds · protein-protein
- I–R · 2709 Ų buried · 38 hydrogen bonds · protein-protein
- B–K · 2694 Ų buried · 32 hydrogen bonds · protein-protein
- D–Y · 2680 Ų buried · 34 hydrogen bonds · protein-protein
- I–K · 368 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 1QX5 · Crystal structure of apoCalmodulin · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62161
- Elsewhere: RCSB PDB 1QX5 · PDBe 1QX5 · UniProt P62161
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