Research workbench
Human estrogenic 17BETA-hydroxysteroid dehydrogenase
Analyse Human estrogenic 17BETA-hydroxysteroid dehydrogenase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1BHS
- Type
- protein
- Length
- 284 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 17BETA-hydroxysteroid dehydrogenase
- EC
- 1.1.1.62
- UniProt
- P14061
- Pockets
- 3 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 17BETA-hydroxysteroid dehydrogenase (EC 1.1.1.62) | protein | 284 | 53% helix, 14% strand | P14061 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 726 | 0.81 | 0.84 | 60 | empty |
| 2 | 82 | 0.36 | 0.75 | 18 | empty |
| 3 | 68 | 0.27 | 0.71 | 21 | empty |
Compared structures
- 1BHS · Human estrogenic 17BETA-hydroxysteroid dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
- P14061 · AlphaFold monomer V2.0 prediction for 17-beta-hydroxysteroid dehydrogenase type 1 (P14061) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14061
- Elsewhere: RCSB PDB 1BHS · PDBe 1BHS · UniProt P14061
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