Research workbench
A mutant shiga-like toxin iie
Analyse A mutant shiga-like toxin iie in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1QOH
- Type
- protein
- Length
- 1,360 residues
- Chains
- 20
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Shiga-like toxin iie B subunit
- UniProt
- Q47644
- Pockets
- 11 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | Shiga-like toxin iie B subunit | protein | 68 | 16% helix, 46% strand | Q47644 |
Pockets
11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1015 | 0.84 | 0.85 | 71 | empty |
| 2 | 1141 | 0.83 | 0.84 | 83 | empty |
| 3 | 1121 | 0.83 | 0.84 | 76 | empty |
| 4 | 914 | 0.82 | 0.84 | 62 | empty |
| 5 | 528 | 0.75 | 0.83 | 63 | empty |
Interfaces
49 interfaces between chains.
- K–L · 694 Ų buried · 12 hydrogen bonds · protein-protein
- M–N · 688 Ų buried · 15 hydrogen bonds · protein-protein
- A–B · 686 Ų buried · 14 hydrogen bonds · protein-protein
- P–T · 683 Ų buried · 15 hydrogen bonds · protein-protein
- C–D · 678 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 20 disulfide (disulfide).
Compared structures
- 1QOH · A mutant shiga-like toxin iie · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q47644
- Elsewhere: RCSB PDB 1QOH · PDBe 1QOH · UniProt Q47644
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.