Research workbench
NMR structure of the 0.5B anti-HIV antibody complex with the GP120 V3 peptide
Analyse NMR structure of the 0.5B anti-HIV antibody complex with the GP120 V3 peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1QNZ
- Type
- protein
- Length
- 249 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 0.5B antibody (heavy chain); 0.5B antibody (light chain); GP120
- UniProt
- P01665, Q79416
Structure
solution nmr · 3 distinct chains · 2% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H | 0.5B antibody (heavy chain) | protein | 119 | 3% helix, 51% strand | — |
| L | 0.5B antibody (light chain) | protein | 112 | 3% helix, 46% strand | P01665 |
| P | GP120 | protein | 18 | 0% helix, 33% strand | Q79416 |
Interfaces
3 interfaces between chains.
- H–L · 846 Ų buried · 11 hydrogen bonds · protein-protein
- H–P · 582 Ų buried · 22 hydrogen bonds · protein-protein
- L–P · 192 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1QNZ · NMR structure of the 0.5b anti-HIV antibody complex with the gp120 V3 peptide · the same entry in another collection · chain H against H, TM-score 1.00
- P01665 · AlphaFold monomer V2.0 prediction for ig kappa chain V-III region pc 7043 (P01665) · a predicted model of the same protein · chain L against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01665
- Every structure of UniProt Q79416
- Elsewhere: RCSB PDB 1QNZ · PDBe 1QNZ · UniProt P01665 · UniProt Q79416
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.