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Topoisomerase residues 410-1202,

Analyse Topoisomerase residues 410-1202, in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1BGW
Type: protein
Length: 679 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Topoisomerase
UniProt: P06786
Pockets: 7 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Topoisomerase	protein	679	43% helix, 15% strand	P06786

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	472	0.66	0.78	38	empty
2	430	0.65	0.78	33	empty
3	216	0.54	0.78	23	empty
4	166	0.47	0.76	28	empty
5	173	0.46	0.75	32	empty

Compared structures

1BGW · Topoisomerase residues 410-1202, · the same entry in another collection · chain A against A, TM-score 1.00
P06786 · AlphaFold monomer V2.0 prediction for DNA topoisomerase 2 (P06786) · a predicted model of the same protein · chain A against A, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06786
Elsewhere: RCSB PDB 1BGW · PDBe 1BGW · UniProt P06786

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