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High resolution NMR structure of the stereoregular (all-rp)- phosphorothioate-DNA/RNA hybrid D (G*PS*C*PS*G*PS*T*PS*C*PS*A*PS*G*PS*G)R(CCUGACGC), minimized average structure

Analyse High resolution NMR structure of the stereoregular (all-rp)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
8PSH
Type
DNA + RNA
Length
16 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*DGP*(SC)P*(GS)P*(PST)P*(SC)P*(AS)P*(GS)P*(GS))- 3'); RNA…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*DGP*(SC)P*(GS)P*(PST)P*(SC)P*(AS)P*(GS)P*(GS))- 3')dna8——
BRNA (5'-R(*CP*CP*UP*GP*AP*CP*GP*C)-3')rna8——

Interfaces

1 interface between chains.

  • A–B · 386 Ų buried · 46 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 7 modified (nucleotide modification).

Compared structures

  • 8PSH · High resolution NMR structure of the stereoregular (all-rp)-phosphorothioate-DNA/RNA… · the same entry in another collection · chain A against A, TM-score 1.00

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