Research workbench
Cryo-EM structure of SARS-cov-2 M protein in a lipid nanodisc
Analyse Cryo-EM structure of SARS-cov-2 M protein in a lipid nanodisc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 8CTK
- Type
- protein
- Length
- 376 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Membrane protein
- UniProt
- P0DTC5
- Pockets
- 2 · best druggability 0.86
Structure
electron microscopy · 1 distinct chain · 44% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Membrane protein | protein | 188 | 44% helix, 29% strand | P0DTC5 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 985 | 0.86 | 0.87 | 73 | empty |
| 2 | 51 | 0.29 | 0.75 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 2398 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 8CTK · Cryo-EM structure of SARS-CoV-2 M protein in a lipid nanodisc · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DTC5
- Elsewhere: RCSB PDB 8CTK · PDBe 8CTK · UniProt P0DTC5
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