Research workbench

Crystal structure of the kinetoplastid kinetochore protein trypanosoma congolense KKT2 divergent polo-box domain

Analyse Crystal structure of the kinetoplastid kinetochore protein trypanosoma… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 8A0J
Type: protein
Length: 440 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein TCIL3000_11_11110
UniProt: G0V1V5
Pockets: 7 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 19% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein TCIL3000_11_11110	protein	223	21% helix, 34% strand	G0V1V5
B	Uncharacterized protein TCIL3000_11_11110	protein	217	17% helix, 35% strand	G0V1V5

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	284	0.56	0.77	41	empty
2	161	0.51	0.78	23	empty
3	171	0.47	0.75	27	empty
4	140	0.46	0.77	22	empty
5	125	0.44	0.77	22	empty

Interfaces

1 interface between chains.

A–B · 540 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

8A0J · Crystal structure of the kinetoplastid kinetochore protein Trypanosoma congolense KKT2… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0V1V5
Elsewhere: RCSB PDB 8A0J · PDBe 8A0J · UniProt G0V1V5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.