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Crystal structure of the C89A_C113A gmp synthetase inactive double mutant from plasmodium falciparum
Analyse Crystal structure of the C89A_C113A gmp synthetase inactive double mutant from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7ZU9
- Type
- protein
- Length
- 509 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamine amidotransferase
- EC
- 6.3.5.2
- UniProt
- Q8IJR9
- Pockets
- 10 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamine amidotransferase (EC 6.3.5.2) | protein | 509 | 22% helix, 11% strand | Q8IJR9 |
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 947 | 0.86 | 0.87 | 111 | empty |
| 2 | 355 | 0.75 | 0.86 | 55 | empty |
| 3 | 182 | 0.68 | 0.87 | 28 | empty |
| 4 | 181 | 0.62 | 0.83 | 30 | empty |
| 5 | 92 | 0.55 | 0.85 | 25 | empty |
Compared structures
- 7ZU9 · Crystal structure of the C89A_C113A gmp synthetase inactive double mutant from plasmodium… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IJR9
- Elsewhere: RCSB PDB 7ZU9 · PDBe 7ZU9 · UniProt Q8IJR9
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