Research workbench
Cryo-EM structure of USP9X, local refinement of monomer
Analyse Cryo-EM structure of USP9X, local refinement of monomer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7YXY
- Type
- protein
- Length
- 1,739 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable ubiquitin carboxyl-terminal hydrolase faf-X
- EC
- 3.4.19.12
- UniProt
- Q93008
- Pockets
- 20 · best druggability 0.67
Structure
electron microscopy · 1 distinct chain · 59% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable ubiquitin carboxyl-terminal hydrolase faf-X (EC 3.4.19.12) | protein | 1739 | 59% helix, 7% strand | Q93008 |
Pockets
20 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.67 | 0.95 | 18 | empty |
| 2 | 51 | 0.61 | 0.93 | 20 | empty |
| 3 | 51 | 0.58 | 0.91 | 17 | empty |
| 4 | 130 | 0.52 | 0.80 | 22 | empty |
| 5 | 64 | 0.52 | 0.86 | 20 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7YXY · Cryo-EM structure of USP9X, local refinement of monomer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93008
- Elsewhere: RCSB PDB 7YXY · PDBe 7YXY · UniProt Q93008
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