Research workbench
Crystal structure of an intramolecular mesacyl-CoA transferase from the 3-hydroxypropionic acid cycle of roseiflexus castenholzii
Analyse Crystal structure of an intramolecular mesacyl-CoA transferase from the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7XKG
- Type
- protein
- Length
- 2,435 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acyl-CoA TRANSFERASE/CARNITINE dehydratase-like protein
- UniProt
- A7NHS9
- Pockets
- 20 · best druggability 0.81
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, E, F | Acyl-CoA TRANSFERASE/CARNITINE dehydratase-like protein | protein | 406 | 40% helix, 16% strand | A7NHS9 |
| D | Acyl-CoA TRANSFERASE/CARNITINE dehydratase-like protein | protein | 405 | 41% helix, 16% strand | A7NHS9 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1135 | 0.81 | 0.82 | 103 | empty |
| 2 | 1106 | 0.80 | 0.81 | 99 | empty |
| 3 | 788 | 0.78 | 0.82 | 64 | empty |
| 4 | 498 | 0.76 | 0.83 | 69 | empty |
| 5 | 558 | 0.75 | 0.82 | 78 | empty |
Interfaces
15 interfaces between chains.
- C–D · 6896 Ų buried · 81 hydrogen bonds · protein-protein
- A–B · 6865 Ų buried · 77 hydrogen bonds · protein-protein
- E–F · 6860 Ų buried · 84 hydrogen bonds · protein-protein
- B–C · 424 Ų buried · 2 hydrogen bonds · protein-protein
- D–E · 421 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 7XKG · Crystal structure of an intramolecular mesacyl-CoA transferase from the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7NHS9
- Elsewhere: RCSB PDB 7XKG · PDBe 7XKG · UniProt A7NHS9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.