Research workbench
Photobacterium phosphoreum fatty acid reductase complex luxc-luxe
Analyse Photobacterium phosphoreum fatty acid reductase complex luxc-luxe in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7XC6
- Type
- protein
- Length
- 2,026 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Luxe; Long-chain acyl-protein thioester reductase
- EC
- 1.2.1.50
- UniProt
- A8R7D1, P19841
- Pockets
- 20 · best druggability 0.87
Structure
electron microscopy · 2 distinct chains · 37% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Luxe | protein | 118 | 27% helix, 19% strand | A8R7D1 |
| A, B, C, D | Long-chain acyl-protein thioester reductase (EC 1.2.1.50) | protein | 477 | 39% helix, 15% strand | P19841 |
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 557 | 0.87 | 0.92 | 79 | empty |
| 2 | 555 | 0.86 | 0.92 | 75 | empty |
| 3 | 536 | 0.86 | 0.92 | 74 | empty |
| 4 | 546 | 0.86 | 0.91 | 74 | empty |
| 5 | 876 | 0.85 | 0.87 | 66 | empty |
Interfaces
7 interfaces between chains.
- C–D · 4839 Ų buried · 90 hydrogen bonds · protein-protein
- A–B · 4827 Ų buried · 92 hydrogen bonds · protein-protein
- A–D · 1096 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 1069 Ų buried · 12 hydrogen bonds · protein-protein
- E–C · 977 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 7XC6 · Photobacterium phosphoreum fatty acid reductase complex LuxC-LuxE · the same entry in another collection · chain E against E, TM-score 1.00
- P19841 · AlphaFold monomer V2.0 prediction for long-chain acyl-protein thioester reductase (P19841) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8R7D1
- Every structure of UniProt P19841
- Elsewhere: RCSB PDB 7XC6 · PDBe 7XC6 · UniProt A8R7D1 · UniProt P19841
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