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Anabolic ornithine carbamoyltransferases (otcs) from psychrobacter sp. pamc 21119

Analyse Anabolic ornithine carbamoyltransferases (otcs) from psychrobacter sp. pamc… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7X99
Type
protein
Length
588 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ornithine carbamoyltransferase
Pockets
8 · best druggability 0.67

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AOrnithine carbamoyltransferaseprotein29447% helix, 15% strand—
BOrnithine carbamoyltransferaseprotein29446% helix, 14% strand—

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12700.670.8341empty
22750.590.7933empty
32110.520.7744empty
41570.520.8023empty
5710.380.7714empty

Interfaces

1 interface between chains.

  • A–B · 688 Ų buried · 11 hydrogen bonds · protein-protein

Compared structures

  • 7X99 · Anabolic ornithine carbamoyltransferases (OTCs) from Psychrobacter sp. PAMC 21119 · the same entry in another collection · chain A against A, TM-score 1.00

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