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Crystal structure of BIT1

Analyse Crystal structure of BIT1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1Q7S
Type: protein
Length: 231 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BIT1
UniProt: Q9Y3E5
Pockets: 2 · best druggability 0.31

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	BIT1	protein	117	47% helix, 28% strand	Q9Y3E5
B	BIT1	protein	114	48% helix, 26% strand	Q9Y3E5

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.31	0.73	15	empty
2	56	0.30	0.76	13	empty

Interfaces

1 interface between chains.

A–B · 1072 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

1Q7S · Crystal structure of bit1 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y3E5 · AlphaFold monomer V2.0 prediction for peptidyl-tRNA hydrolase 2, mitochondrial (Q9Y3E5) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y3E5
Elsewhere: RCSB PDB 1Q7S · PDBe 1Q7S · UniProt Q9Y3E5

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