Research workbench
Adeno-associated virus serotype 9 in complex with aavr
Analyse Adeno-associated virus serotype 9 in complex with aavr in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7WJX
- Type
- protein
- Length
- 613 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dyslexia-associated protein KIAA0319-like protein; Capsid protein VP1
- UniProt
- Q8IZA0, Q6JC40
- Pockets
- 8 · best druggability 0.63
Structure
electron microscopy · 2 distinct chains · 5% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| R | Dyslexia-associated protein KIAA0319-like protein | protein | 95 | 0% helix, 44% strand | Q8IZA0 |
| A | Capsid protein VP1 | protein | 518 | 5% helix, 32% strand | Q6JC40 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 513 | 0.63 | 0.75 | 65 | empty |
| 2 | 341 | 0.58 | 0.76 | 48 | empty |
| 3 | 155 | 0.41 | 0.74 | 23 | empty |
| 4 | 109 | 0.39 | 0.75 | 21 | empty |
| 5 | 102 | 0.39 | 0.76 | 23 | empty |
Interfaces
1 interface between chains.
- R–A · 648 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 7WJX · Adeno-associated virus serotype 9 in complex with AAVR · the same entry in another collection · chain R against R, TM-score 1.00
- Q8IZA0 · AlphaFold monomer V2.0 prediction for dyslexia-associated protein KIAA0319-like protein… · a predicted model of the same protein · chain R against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IZA0
- Every structure of UniProt Q6JC40
- Elsewhere: RCSB PDB 7WJX · PDBe 7WJX · UniProt Q8IZA0 · UniProt Q6JC40
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