Research workbench
The apo structure of trichobrasilenol synthase TATC6 with the space group of monoclinic
Analyse The apo structure of trichobrasilenol synthase TATC6 with the space group of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7W5F
- Type
- protein
- Length
- 677 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Terpene cyclase 6
- EC
- 4.2.3.-, 4.2.3.104, 4.2.3.137, 4.2.3.157, 4.2.3.182, 4.2.3.57
- UniProt
- A0A5S9I252
- Ligands
- MG
- Pockets
- 5 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 68% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Terpene cyclase 6 (EC 4.2.3.-, 4.2.3.104, 4.2.3.137, 4.2.3.157, 4.2.3.182, 4.2.3.57) | protein | 339 | 68% helix, 3% strand | A0A5S9I252 |
| B | Terpene cyclase 6 (EC 4.2.3.-, 4.2.3.104, 4.2.3.137, 4.2.3.157, 4.2.3.182, 4.2.3.57) | protein | 338 | 68% helix, 3% strand | A0A5S9I252 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 535 | 0.76 | 0.83 | 46 | MG |
| 2 | 667 | 0.75 | 0.81 | 48 | empty |
| 3 | 525 | 0.71 | 0.80 | 64 | empty |
| 4 | 136 | 0.46 | 0.77 | 14 | empty |
| 5 | 99 | 0.38 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 910 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7W5F · The apo structure of trichobrasilenol synthase TaTC6 with the space group of monoclinic · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A5S9I252
- Elsewhere: RCSB PDB 7W5F · PDBe 7W5F · UniProt A0A5S9I252
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