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Tetrameric antiparallel G-quadruplex formed by natural human telomeric sequence

Analyse Tetrameric antiparallel G-quadruplex formed by natural human telomeric sequence in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7W0X
Type
DNA
Length
24 nucleotides
Chains
4
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*GP*GP*GP*TP*TP*A)-3')

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, DDNA (5'-D(*GP*GP*GP*TP*TP*A)-3')dna6——

Interfaces

6 interfaces between chains.

  • A–C · 208 Ų buried · 12 hydrogen bonds · nucleic-nucleic
  • B–D · 207 Ų buried · 12 hydrogen bonds · nucleic-nucleic
  • C–D · 204 Ų buried · 6 hydrogen bonds · nucleic-nucleic
  • A–D · 197 Ų buried · 12 hydrogen bonds · nucleic-nucleic
  • B–C · 196 Ų buried · 12 hydrogen bonds · nucleic-nucleic

Compared structures

  • 7W0X · Tetrameric antiparallel G-quadruplex formed by natural human telomeric sequence · the same entry in another collection · chain A against A, TM-score 1.00

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