Research workbench

Acyltransferase from the 9TH module of salinomycin polyketide synthase

Analyse Acyltransferase from the 9TH module of salinomycin polyketide synthase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7VT1
Type: protein
Length: 870 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Type I modular polyketide synthase
UniProt: H1ZZT7
Pockets: 6 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Type I modular polyketide synthase	protein	433	45% helix, 15% strand	H1ZZT7
B	Type I modular polyketide synthase	protein	437	46% helix, 15% strand	H1ZZT7

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	282	0.69	0.84	40	empty
2	304	0.69	0.83	43	empty
3	643	0.63	0.74	59	empty
4	55	0.30	0.76	15	empty
5	53	0.27	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 152 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

7VT1 · Acyltransferase from the 9th Module of Salinomycin Polyketide Synthase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt H1ZZT7
Elsewhere: RCSB PDB 7VT1 · PDBe 7VT1 · UniProt H1ZZT7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.