Research workbench
Structure of the human BRG1/SS18 complex
Analyse Structure of the human BRG1/SS18 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7VRB
- Type
- protein
- Length
- 435 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SMARCA4 PROTEIN,PROTEIN ssxt
- UniProt
- B9EGQ8, Q15532
- Pockets
- 5 · best druggability 0.68
Structure
x-ray diffraction · 3 distinct chains · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SMARCA4 PROTEIN,PROTEIN ssxt | protein | 112 | 68% helix, 0% strand | B9EGQ8, Q15532 |
| B, C | SMARCA4 PROTEIN,PROTEIN ssxt | protein | 109 | 68% helix, 0% strand | B9EGQ8, Q15532 |
| D | SMARCA4 PROTEIN,PROTEIN ssxt | protein | 105 | 74% helix, 0% strand | B9EGQ8, Q15532 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 139 | 0.68 | 0.89 | 29 | empty |
| 2 | 98 | 0.45 | 0.79 | 19 | empty |
| 3 | 104 | 0.44 | 0.78 | 13 | empty |
| 4 | 56 | 0.42 | 0.82 | 19 | empty |
| 5 | 74 | 0.38 | 0.78 | 14 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1274 Ų buried · 17 hydrogen bonds · protein-protein
- B–C · 1064 Ų buried · 9 hydrogen bonds · protein-protein
- A–D · 925 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B9EGQ8
- Every structure of UniProt Q15532
- Elsewhere: RCSB PDB 7VRB · PDBe 7VRB · UniProt B9EGQ8 · UniProt Q15532
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