Research workbench
Crystal structure of ef-TU/CDIA/CDII
Analyse Crystal structure of ef-TU/CDIA/CDII in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7VMC
- Type
- protein
- Length
- 672 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Elongation factor tu; TRNA nuclease cdia; Contact-dependent inhibitor I
- EC
- 3.1.-.-
- UniProt
- E2QJ06, B3BM48, A0A2A3ULE6
- Pockets
- 11 · best druggability 0.76
Structure
x-ray diffraction · 3 distinct chains · 21% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Elongation factor tu | protein | 384 | 21% helix, 35% strand | E2QJ06 |
| B | TRNA nuclease cdia (EC 3.1.-.-) | protein | 111 | 34% helix, 26% strand | B3BM48 |
| C | Contact-dependent inhibitor I | protein | 177 | 10% helix, 38% strand | A0A2A3ULE6 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 86 | 0.76 | 0.97 | 26 | empty |
| 2 | 636 | 0.67 | 0.77 | 60 | empty |
| 3 | 267 | 0.63 | 0.81 | 40 | empty |
| 4 | 102 | 0.63 | 0.87 | 23 | empty |
| 5 | 282 | 0.56 | 0.77 | 34 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1247 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 995 Ų buried · 16 hydrogen bonds · protein-protein
- A–C · 21 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7VMC · Crystal structure of EF-Tu/CdiA/CdiI · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E2QJ06
- Every structure of UniProt B3BM48
- Every structure of UniProt A0A2A3ULE6
- Elsewhere: RCSB PDB 7VMC · PDBe 7VMC · UniProt E2QJ06 · UniProt B3BM48 · UniProt A0A2A3ULE6
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