Research workbench
Type I-F anti-CRISPR protein ACRIF13
Analyse Type I-F anti-CRISPR protein ACRIF13 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7VEH
- Type
- protein
- Length
- 934 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ACRIF13
- UniProt
- A0A3A9QXE8
- Pockets
- 14 · best druggability 0.77
Structure
x-ray diffraction · 4 distinct chains · 25% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D, F, G | ACRIF13 | protein | 118 | 25% helix, 30% strand | A0A3A9QXE8 |
| B, C | ACRIF13 | protein | 115 | 25% helix, 30% strand | A0A3A9QXE8 |
| E | ACRIF13 | protein | 115 | 25% helix, 31% strand | A0A3A9QXE8 |
| H | ACRIF13 | protein | 117 | 25% helix, 26% strand | A0A3A9QXE8 |
Pockets
14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 285 | 0.77 | 0.89 | 30 | empty |
| 2 | 376 | 0.76 | 0.87 | 44 | empty |
| 3 | 278 | 0.76 | 0.88 | 36 | empty |
| 4 | 245 | 0.71 | 0.86 | 32 | empty |
| 5 | 185 | 0.57 | 0.81 | 36 | empty |
Interfaces
9 interfaces between chains.
- A–D · 648 Ų buried · 13 hydrogen bonds · protein-protein
- B–G · 640 Ų buried · 10 hydrogen bonds · protein-protein
- B–C · 609 Ų buried · 11 hydrogen bonds · protein-protein
- A–E · 608 Ų buried · 7 hydrogen bonds · protein-protein
- C–D · 601 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 7VEH · Type I-F Anti-CRISPR protein AcrIF13 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A3A9QXE8
- Elsewhere: RCSB PDB 7VEH · PDBe 7VEH · UniProt A0A3A9QXE8
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