Research workbench
Crystal structure of heterotetrameric complex of SA2YOEB-SA2YEFM toxin-antitoxin from staphylococcus aureus
Analyse Crystal structure of heterotetrameric complex of SA2YOEB-SA2YEFM… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7V5Z
- Type
- protein
- Length
- 344 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Antitoxin; Putative mRNA interferase yoeb
- UniProt
- Q2FVF7, Q2FVF8
- Pockets
- 5 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Antitoxin | protein | 85 | 58% helix, 16% strand | Q2FVF7 |
| C, D | Putative mRNA interferase yoeb | protein | 87 | 32% helix, 29% strand | Q2FVF8 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.41 | 0.73 | 26 | empty |
| 2 | 96 | 0.40 | 0.77 | 14 | empty |
| 3 | 87 | 0.33 | 0.74 | 16 | empty |
| 4 | 62 | 0.30 | 0.75 | 13 | empty |
| 5 | 57 | 0.27 | 0.73 | 15 | empty |
Interfaces
5 interfaces between chains.
- A–C · 1711 Ų buried · 32 hydrogen bonds · protein-protein
- B–D · 1629 Ų buried · 43 hydrogen bonds · protein-protein
- A–B · 1565 Ų buried · 30 hydrogen bonds · protein-protein
- B–C · 137 Ų buried · 0 hydrogen bonds · protein-protein
- A–D · 127 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7V5Z · Crystal structure of heterotetrameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2FVF7
- Every structure of UniProt Q2FVF8
- Elsewhere: RCSB PDB 7V5Z · PDBe 7V5Z · UniProt Q2FVF7 · UniProt Q2FVF8
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