Research workbench
Lysr family transcriptional regulator ripr from salmonella typhimurium
Analyse Lysr family transcriptional regulator ripr from salmonella typhimurium in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7V5V
- Type
- protein
- Length
- 822 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ripr
- UniProt
- Q93DX4
- Pockets
- 5 · best druggability 0.71
Structure
x-ray diffraction · 4 distinct chains · 36% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ripr | protein | 207 | 35% helix, 27% strand | Q93DX4 |
| B | Ripr | protein | 207 | 37% helix, 27% strand | Q93DX4 |
| C | Ripr | protein | 203 | 36% helix, 31% strand | Q93DX4 |
| D | Ripr | protein | 205 | 36% helix, 31% strand | Q93DX4 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1184 | 0.71 | 0.75 | 106 | empty |
| 2 | 187 | 0.63 | 0.84 | 34 | empty |
| 3 | 232 | 0.62 | 0.81 | 32 | empty |
| 4 | 106 | 0.36 | 0.74 | 21 | empty |
| 5 | 99 | 0.36 | 0.74 | 21 | empty |
Interfaces
5 interfaces between chains.
- B–C · 1394 Ų buried · 24 hydrogen bonds · protein-protein
- A–D · 1352 Ų buried · 25 hydrogen bonds · protein-protein
- C–D · 227 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 89 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 39 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 7V5V · LysR family transcriptional regulator RipR from Salmonella Typhimurium · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93DX4
- Elsewhere: RCSB PDB 7V5V · PDBe 7V5V · UniProt Q93DX4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.