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The crystal structure of the K36A/K137A double mutant of E. COLI yggs in complex with plp

Analyse The crystal structure of the K36A/K137A double mutant of E. COLI yggs in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7UBP
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pyridoxal phosphate homeostasis protein
UniProt: C3SV52
Ligands: PLP, SO4
Pockets: 3 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pyridoxal phosphate homeostasis protein	protein	226	47% helix, 18% strand	C3SV52

Ligands and binding sites

PLP · Pyridoxal-5'-phosphate · ligand · 2 copies · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	93	0.42	0.78	22	empty
2	85	0.36	0.75	17	PLP
3	66	0.32	0.76	13	empty

Compared structures

7UBP · The crystal structure of the K36A/K137A double mutant of E. coli YGGS in complex with PLP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C3SV52
Elsewhere: RCSB PDB 7UBP · PDBe 7UBP · UniProt C3SV52

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