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The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. COLI yggs in complex with plp

Analyse The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. COLI… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7UB4
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pyridoxal phosphate homeostasis protein
UniProt: C3SV52
Ligands: PLP
Pockets: 3 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pyridoxal phosphate homeostasis protein	protein	226	47% helix, 18% strand	C3SV52

Ligands and binding sites

PLP · Pyridoxal-5'-phosphate · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.41	0.81	20	empty
2	68	0.30	0.74	15	PLP
3	51	0.28	0.75	16	empty

Compared structures

7UB4 · The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. coli YGGS in… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C3SV52
Elsewhere: RCSB PDB 7UB4 · PDBe 7UB4 · UniProt C3SV52

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