Research workbench
Crystal structure of human cholesterol sulfotransferase (SULT2B1B) in the presence of pap
Analyse Crystal structure of human cholesterol sulfotransferase (SULT2B1B) in the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1Q1Z
- Type
- protein
- Length
- 284 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sulfotransferase family, cytosolic, 2B, member 1 isoform B
- UniProt
- O00204
- Ligands
- A3P, NA
- Pockets
- 2 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sulfotransferase family, cytosolic, 2B, member 1 isoform B | protein | 284 | 45% helix, 12% strand | O00204 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 370 | 0.78 | 0.87 | 47 | A3P |
| 2 | 61 | 0.34 | 0.77 | 14 | empty |
Compared structures
- 1Q1Z · Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of PAP · the same entry in another collection · chain A against A, TM-score 1.00
- O00204 · AlphaFold monomer V2.0 prediction for sulfotransferase 2B1 (O00204) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00204
- Elsewhere: RCSB PDB 1Q1Z · PDBe 1Q1Z · UniProt O00204
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