Cyanophycin synthetase 1 from synechocystis sp. UTEX2470 E82Q with ATP and 16X(ASP-arg)

Structure

electron microscopy · 3 distinct chains · 33% helix, 21% strand (DSSP).

Ligands and binding sites

• ATP · Adenosine-5'-triphosphate · ligand · 8 copies · chains A, B, C, D
• MG · Magnesium ion · metal · 16 copies · chains A, B, C, D
• ZN · Zinc ion · metal · 4 copies · chains A, I, B, J, C, K, D, L
• 7ID · (2~{S})-4-[[(2~{S})-5-[[azanyl($l^{4}-azanylidene) methyl]amino]-1-$L^{1}-oxidanyl-1-oxidanylidene-pentan-2-yl]amino]-2-$L^{2}-azanyl-4-oxidanylidene-butanoic acid · ion · 4 copies · chains A, I, B, J, C, K, D, L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Interfaces

16 interfaces between chains.

• A–B · 1757 Ų buried · 11 hydrogen bonds · protein-protein
• C–D · 1719 Ų buried · 8 hydrogen bonds · protein-protein
• C–K · 1095 Ų buried · 36 hydrogen bonds · protein-protein
• A–I · 1095 Ų buried · 37 hydrogen bonds · protein-protein
• D–L · 1090 Ų buried · 37 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 44 modified (nonstandard).

Compared structures

• 7TXV · Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 E82Q with ATP and 16x(Asp-Arg) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A068N621
• Elsewhere: RCSB PDB 7TXV · PDBe 7TXV · UniProt A0A068N621