Research workbench
Crystal structure of yeast P58C multi-tyrosine mutant 5YF431
Analyse Crystal structure of yeast P58C multi-tyrosine mutant 5YF431 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7TL3
- Type
- protein
- Length
- 184 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA primase large subunit
- UniProt
- A0A7I9C0U2
- Ligands
- SF4
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 65% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA primase large subunit | protein | 184 | 65% helix, 0% strand | A0A7I9C0U2 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 122 | 0.64 | 0.87 | 23 | SF4, MPD |
| 2 | 65 | 0.30 | 0.74 | 16 | MPD |
Modifications
Observed in the structure: 1 covalent (additive adduct).
Compared structures
- 7TL3 · Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A7I9C0U2
- Elsewhere: RCSB PDB 7TL3 · PDBe 7TL3 · UniProt A0A7I9C0U2
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