Research workbench
L. monocytogenes GS(12) - apo
Analyse L. monocytogenes GS(12) - apo in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7TFE
- Type
- protein
- Length
- 5,316 residues
- Chains
- 12
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamine synthetase
- EC
- 6.3.1.2
- UniProt
- A0A5D5GA79
- Ligands
- MG
- Pockets
- 20 · best druggability 0.79
Structure
electron microscopy · 1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, G, H, I, B, C, J, D, E, F, K, L | Glutamine synthetase (EC 6.3.1.2) | protein | 443 | 39% helix, 21% strand | A0A5D5GA79 |
Ligands and binding sites
- MG · Magnesium ion · metal · 24 copies · chains A, G, H, I, B, C, J, D, E, F, K, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 707 | 0.79 | 0.83 | 72 | empty |
| 2 | 703 | 0.78 | 0.83 | 63 | empty |
| 3 | 706 | 0.78 | 0.82 | 66 | empty |
| 4 | 662 | 0.78 | 0.83 | 69 | empty |
| 5 | 680 | 0.77 | 0.83 | 65 | empty |
Interfaces
24 interfaces between chains.
- A–F · 2165 Ų buried · 20 hydrogen bonds · protein-protein
- G–L · 2165 Ų buried · 18 hydrogen bonds · protein-protein
- I–J · 2153 Ų buried · 21 hydrogen bonds · protein-protein
- C–D · 2147 Ų buried · 21 hydrogen bonds · protein-protein
- H–K · 2141 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 7TFE · L. monocytogenes GS(12) - apo · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A5D5GA79
- Elsewhere: RCSB PDB 7TFE · PDBe 7TFE · UniProt A0A5D5GA79
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.