Crystal structure of the ZN(II) form of E. COLI zntr, a zinc-sensing transcriptional regulator, at 1.9 a resolution (space group P212121)

Structure

x-ray diffraction · 2 distinct chains · 80% helix, 2% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · 4 copies · chains A, B
• MG · Magnesium ion · metal · chains A
• PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 2428 Ų buried · 32 hydrogen bonds · protein-protein

Compared structures

• 1Q08 · Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional… · the same entry in another collection · chain A against A, TM-score 1.00
• P0ACS5 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator zntr (P0ACS5) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P0ACS5
• Elsewhere: RCSB PDB 1Q08 · PDBe 1Q08 · UniProt P0ACS5