Research workbench
Phosphotriesterase homology protein from escherichia COLI
Analyse Phosphotriesterase homology protein from escherichia COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1BF6
- Type
- protein
- Length
- 582 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphotriesterase homology protein
- UniProt
- P45548
- Ligands
- ZN, SO4
- Pockets
- 5 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Phosphotriesterase homology protein | protein | 291 | 50% helix, 16% strand | P45548 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains A, B
- SO4 · Sulfate ion · ion · 2 copies · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A, B
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 270 | 0.63 | 0.81 | 26 | SO4 |
| 2 | 236 | 0.61 | 0.81 | 24 | ZN |
| 3 | 73 | 0.35 | 0.75 | 10 | MPD |
| 4 | 85 | 0.34 | 0.74 | 18 | empty |
| 5 | 77 | 0.29 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 255 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 1BF6 · Phosphotriesterase homology protein from escherichia COLI · the same entry in another collection · chain A against A, TM-score 1.00
- P45548 · AlphaFold monomer V2.0 prediction for phosphotriesterase homology protein (P45548) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45548
- Elsewhere: RCSB PDB 1BF6 · PDBe 1BF6 · UniProt P45548
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.