Research workbench

Crystal structure of L-galactose dehydrogenase from spinacia oleracea in complex with NAD+

Analyse Crystal structure of L-galactose dehydrogenase from spinacia oleracea in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7SVQ
Type: protein
Length: 630 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-galactose dehydrogenase
UniProt: Q6BDJ2
Ligands: NAD
Pockets: 5 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	L-galactose dehydrogenase	protein	315	46% helix, 17% strand	Q6BDJ2

Ligands and binding sites

NAD · Nicotinamide-adenine-dinucleotide · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	710	0.82	0.85	79	NAD
2	438	0.73	0.83	53	NAD
3	97	0.37	0.75	18	empty
4	54	0.29	0.75	16	empty
5	58	0.28	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 701 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

7SVQ · Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea in complex with NAD+ · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6BDJ2
Elsewhere: RCSB PDB 7SVQ · PDBe 7SVQ · UniProt Q6BDJ2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.