The X-ray crystal structure of the N-terminal domain of staphylococcus aureus fatty acid kinase a (faka, residues 1-208) in complex with AMP and ADP to 1.105 ångström resolution

Structure

x-ray diffraction · 1 distinct chain · 68% helix, 1% strand (DSSP).

Ligands and binding sites

• AMP · Adenosine monophosphate · ligand · chains A
• ADP · Adenosine-5'-diphosphate · ligand · chains A
• MG · Magnesium ion · metal · 4 copies · chains A
• GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 7SNB · The X-ray crystal structure of the N-terminal domain of Staphylococcus aureus Fatty Acid… · the same entry in another collection · chain A against A, TM-score 1.00
• Q7A5Z4 · AlphaFold monomer V2.0 prediction for uncharacterized protein SA1069 (Q7A5Z4) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q7A5Z4
• Elsewhere: RCSB PDB 7SNB · PDBe 7SNB · UniProt Q7A5Z4